HIV-1 Pr55Gagbinds genomic and spliced RNAs with different affinity and stoichiometry

Volume: 14, Issue: 1, Pages: 90 - 103
Published: Dec 18, 2016
Abstract
The HIV-1 Pr55Gag precursor specifically selects genomic RNA (gRNA) from a large variety of cellular and spliced viral RNAs (svRNAs), however the molecular mechanisms of this selective recognition remains poorly understood. To gain better understanding of this process, we analyzed the interactions between Pr55Gag and a large panel of viral RNA (vRNA) fragments encompassing the main packaging signal (Psi) and its flanking regions by fluorescence...
Paper Details
Title
HIV-1 Pr55Gagbinds genomic and spliced RNAs with different affinity and stoichiometry
Published Date
Dec 18, 2016
Volume
14
Issue
1
Pages
90 - 103
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