Coordination of DNA single strand break repair
Abstract
The genetic material of all organisms is susceptible to modification. In some instances, these changes are programmed, such as the formation of DNA double strand breaks during meiotic recombination to generate gamete variety or class switch recombination to create antibody diversity. However, in most cases, genomic damage is potentially harmful to the health of the organism, contributing to disease and aging by promoting deleterious cellular...
Paper Details
Title
Coordination of DNA single strand break repair
Published Date
Jun 1, 2017
Volume
107
Pages
228 - 244
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