Robust, universal biomarker assay to detect senescent cells in biological specimens

Volume: 16, Issue: 1, Pages: 192 - 197
Published: Feb 1, 2017
Abstract
Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin-linked Sudan Black B (SBB) analogue suitable for sensitive and specific, antibody-enhanced detection of lipofuscin-containing senescent cells in any biological material. This new hybrid histo-/immunochemical method is easy to...
Paper Details
Title
Robust, universal biomarker assay to detect senescent cells in biological specimens
Published Date
Feb 1, 2017
Journal
Volume
16
Issue
1
Pages
192 - 197
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