Th9 cells in the pathogenesis of EAE and multiple sclerosis
Abstract
Interleukin (IL)-9 producing CD4+ T helper cells (Th9) are the newest addition to the T helper cell subsets. IL-9 binds to a heterodimeric receptor consisting of the IL-9 receptor (IL-9R) and a common γ chain also presents in IL-2, IL-4, IL-7, and IL-15 receptor complexes. In addition to Th9 cells, Th17 cells secrete smaller amounts of IL-9. Many functional and regulatory roles associated with Th9 cells are currently not fully understood. IL-9...
Paper Details
Title
Th9 cells in the pathogenesis of EAE and multiple sclerosis
Published Date
Nov 14, 2016
Journal
Volume
39
Issue
1
Pages
79 - 87
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Notes
History