Fabrication of functionalized porous silica nanoparticles and their controlled release behavior
Abstract
Thiol and amine difunctionalized porous silica (pSiO2-SH/NH2) nanoparticles (NPs) were prepared by condensation. The obtained pSiO2-SH/NH2 NPs present uniform spheres with size of 55 nm. Folic acid (FA) as a tumor targeting agent was conjugated on the surface of pSiO2 NPs by amide linkage (pSiO2-SH/FA NPs), and captopril (Cap) as test drug was used to evaluate the releasing behavior. Results indicated that Cap is easily encapsulated into the...
Paper Details
Title
Fabrication of functionalized porous silica nanoparticles and their controlled release behavior
Published Date
Feb 1, 2017
Volume
37
Pages
38 - 45
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