Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development
Abstract
Every major biopharmaceutical company incorporates a protein crystallography unit that is central to its structure-based drug discovery efforts. Yet these capabilities are rarely leveraged toward the formal higher order structural characterization that is so challenging but integral to large-scale biologics manufacturing. Although the biotech industry laments the shortcomings of its favored biophysical techniques, x-ray crystallography is not...
Paper Details
Title
Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development
Published Date
Feb 1, 2017
Volume
106
Issue
2
Pages
477 - 494
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