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White matter correlates of psychosis-linked traits support continuity between personality and psychopathology

Published on Jan 1, 2016in Journal of Abnormal Psychology 5.52
· DOI :10.1037/abn0000176
Rachael G. Grazioplene9
Estimated H-index: 9
(UMN: University of Minnesota),
Robert S. Chavez12
Estimated H-index: 12
(OSU: Ohio State University)
+ 1 AuthorsColin G. DeYoung38
Estimated H-index: 38
(UMN: University of Minnesota)
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  • References (24)
  • Citations (7)
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References24
Newest
Published on Feb 1, 2016in Journal of Clinical Neuroscience 1.59
Charles B. Malpas8
Estimated H-index: 8
,
Sila Genc8
Estimated H-index: 8
(University of Melbourne)
+ 3 AuthorsTerence J. O’Brien58
Estimated H-index: 58
(University of Melbourne)
There is growing interest in the neurobiological substrate of general intelligence. Psychometric estimates of general intelligence are reduced in a range of neurological disorders, leading to practical application as sensitive, but non-specific, markers of cerebral disorder. This study examined estimates of general intelligence in neurotypical adults using diffusion tensor imaging and resting-state functional connectivity analysis. General intelligence was related to white matter organisation ac...
Published on Apr 10, 2015in Journal of Individual Differences 1.14
Phillip Grant11
Estimated H-index: 11
,
Aisha Judith Leila Munk3
Estimated H-index: 3
+ 2 AuthorsJuergen Hennig37
Estimated H-index: 37
Schizotypy is an organization of traits mirroring psychosis-like symptoms and conveying individual psychosis-proneness. Schizotypy and schizophrenia share a genetic basis, wherefore initial schizotypy definitions considered a schizophrenic genotype as a condicio sine qua non. Since the search for a monogenetic schizotypy marker has proven in vain, it is believed that schizotypy is (genetically) based on multiple alleles, each of small effect-size. Schizophrenia may be viewed as a qualitative ent...
Published on Mar 1, 2015in Schizophrenia Research 4.57
Naoyuki Katagiri5
Estimated H-index: 5
(Toho University),
Christos Pantelis96
Estimated H-index: 96
(University of Melbourne)
+ 13 AuthorsIssei Fukunaga8
Estimated H-index: 8
(Juntendo University)
Abstract Background Evidence supports disruption in white matter (WM) connectivity in established schizophrenia, however, it is unclear when these abnormalities occur during the course of illness and if they are progressive. Here we investigated whether WM abnormalities predate illness onset by examining a group of individuals with an ‘at risk mental state’ (ARMS) and assess whether there is evidence of progressive change. We hypothesized that WM abnormalities are associated with symptom change....
Published on Feb 1, 2015in Molecular Psychiatry 11.97
Ks Kendler1
Estimated H-index: 1
This essay traces the history of concepts of genetic variation and schizophrenia from Darwin and Mendel to the present. For Darwin, the important form of genetic variation for evolution is continuous in nature and small in effect. Biometricians led by Pearson agreed and developed statistical genetic approaches utilizing trait correlations in relatives. Mendel studied discontinuous traits and subsequent Mendelians, led by Bateson, assumed that important genetic variation was large in effect produ...
Published on Feb 1, 2015in Schizophrenia Research 4.57
Hidayet E. Arat1
Estimated H-index: 1
(Dokuz Eylül University),
Virginie-Anne Chouinard11
Estimated H-index: 11
(Harvard University)
+ 2 AuthorsDost Öngür44
Estimated H-index: 44
(Harvard University)
Objectives White matter (WM) abnormalities are one of the most widely and consistently reported findings in schizophrenia (SZ) and bipolar disorder (BD). If these abnormalities are inherited determinants of illness, suitable to be classified as an endophenotype, relatives of patients must also have them at higher rate compared to the general population. In this review, we evaluate published diffusion tensor imaging (DTI) studies comparing first degree relatives of SZ and BD patients and healthy ...
Published on Jan 1, 2015in Journal of Abnormal Psychology 5.52
Takakuni Suzuki4
Estimated H-index: 4
(Purdue University),
Douglas B. Samuel24
Estimated H-index: 24
(Purdue University)
+ 1 AuthorsRobert F. Krueger91
Estimated H-index: 91
Published on Jan 1, 2015in Psychological Assessment 3.47
Jaime L. Anderson10
Estimated H-index: 10
(UA: University of Alabama),
Martin Sellbom15
Estimated H-index: 15
(ANU: Australian National University)
+ 3 AuthorsR. Michael Bagby66
Estimated H-index: 66
(U of T: University of Toronto)
Our aim in the current study was to evaluate the convergence between Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) Section III dimensional personality traits, as operationalized via the Personality Inventory for DSM-5 (PID-5), and Minnesota Multiphasic Personality Inventory 2–Restructured Form (MMPI-2-RF) scale scores in a psychiatric patient sample. We used a sample of 346 (171 men, 175 women) patients who were recruited through a university-affiliated psychiatric...
Published on Aug 1, 2014in Journal of Personality Disorders 2.97
Michael Chmielewski16
Estimated H-index: 16
(SMU: Southern Methodist University),
R. Michael Bagby66
Estimated H-index: 66
+ 2 AuthorsAndrew G. Ryder28
Estimated H-index: 28
Section III of DSM-5 includes an alternative model for personality disorders comprising five higher-order pathological personality traits, four of which resemble domains from the Big Five/Five-Factor Model of Personality (FFM). There has, however, been considerable debate regarding the association of FFM Openness-to-Experience/Intellect (OE/I) with DSM-5 Psychoticism and Schizotypal Personality Disorder (STPD). The authors identify several limitations in the literature, including inattention to ...
Published on Jan 2, 2014in Journal of Personality Assessment 2.83
Colin G. DeYoung38
Estimated H-index: 38
(UMN: University of Minnesota),
Lena C. Quilty28
Estimated H-index: 28
(U of T: University of Toronto)
+ 1 AuthorsJeremy R. Gray36
Estimated H-index: 36
(Yale University)
An instrument designed to separate 2 midlevel traits within each of the Big Five (the Big Five Aspect Scales [BFAS]) was used to clarify the relation of personality to cognitive ability. The BFAS measures Openness to Experience and Intellect as separate (although related) traits, and refers to the broader Big Five trait as Openness/Intellect. In 2 samples (N = 125 and 189), Intellect was independently associated with general intelligence (g) and with verbal and nonverbal intelligence about equal...
Published on Aug 1, 2013in American Journal of Psychiatry 13.65
Pawel Skudlarski60
Estimated H-index: 60
(UMB: University of Maryland, Baltimore),
Dj Schretlen2
Estimated H-index: 2
(UMB: University of Maryland, Baltimore)
+ 7 AuthorsGodfrey D. Pearlson106
Estimated H-index: 106
(UMB: University of Maryland, Baltimore)
ObjectiveBoth schizophrenia and bipolar disorder are hypothesized to involve disordered brain connectivity. Prior studies show low white matter integrity, measured with diffusion tensor imaging, for both disorders. The authors studied disease specificity and endophenotypic status of these abnormalities by examining patients and their unaffected relatives.MethodThe 513 participants included probands with schizophrenia, probands with psychotic bipolar disorder, their first-degree relatives, and he...
Cited By7
Newest
Published on Jun 10, 2019in Brain Imaging and Behavior 3.42
Stijn Michielse4
Estimated H-index: 4
(Maastricht University Medical Centre),
Iris Lange6
Estimated H-index: 6
(Maastricht University Medical Centre)
+ 8 AuthorsJim van Os4
Estimated H-index: 4
(Maastricht University Medical Centre)
Group comparisons of individuals with psychotic disorder and controls have shown alterations in white matter microstructure. Whether white matter microstructure and network connectivity is altered in adolescents with subclinical psychotic experiences (PE) at the lowest end of the psychosis severity spectrum is less clear. DWI scan were acquired in 48 individuals with PE and 43 healthy controls (HC). Traditional tensor-derived indices: Fractional Anisotropy, Axial Diffusivity, Mean Diffusivity an...
Published on Apr 3, 2019in Psychophysiology 3.38
Lauren Delaparte4
Estimated H-index: 4
(SBU: Stony Brook University),
Elizabeth Bartlett2
Estimated H-index: 2
(SBU: Stony Brook University)
+ 5 AuthorsRoman Kotov36
Estimated H-index: 36
(SBU: Stony Brook University)
Published on Feb 9, 2019in Schizophrenia Bulletin 7.29
David C. Cicero15
Estimated H-index: 15
(U.H.: University of Hawaii at Manoa),
Katherine G. Jonas4
Estimated H-index: 4
(SBU: Stony Brook University)
+ 2 AuthorsRoman Kotov36
Estimated H-index: 36
(SBU: Stony Brook University)
Published on Oct 15, 2018in Schizophrenia Bulletin 7.29
Anna R. Docherty12
Estimated H-index: 12
(VCU: Virginia Commonwealth University),
Eduardo Fonseca-Pedrero20
Estimated H-index: 20
(UR: University of La Rioja)
+ 42 AuthorsOliver Mason26
Estimated H-index: 26
(University of Surrey)
The latent structure of schizotypy and psychosis-spectrum symptoms remains poorly understood. Furthermore, molecular genetic substrates are poorly defined, largely due to the substantial resources required to collect rich phenotypic data across diverse populations. Sample sizes of phenotypic studies are often insufficient for advanced structural equation modeling approaches. In the last 50 years, efforts in both psychiatry and psychological science have moved toward (1) a dimensional model of ps...
Published on Jul 3, 2018in Psychological Inquiry 10.27
Colin G. DeYoung38
Estimated H-index: 38
(UMN: University of Minnesota),
Robert F. Krueger91
Estimated H-index: 91
(UMN: University of Minnesota)
AbstractCybernetics, the study of principles governing goal-directed, self-regulating systems, offers a useful approach to understanding psychopathology or psychological dysfunction, overcoming limitations of other naturalistic approaches. Whereas influential theories of psychopathology have relied on definitions of dysfunction rooted in evolution and fitness, we define psychopathology in terms of cybernetic dysfunction, failure to make progress toward important goals. Cybernetic function in org...
Published on Jul 1, 2018in Human Brain Mapping 4.55
Oshin Vartanian18
Estimated H-index: 18
(U of T: University of Toronto),
Christopher J. Wertz4
Estimated H-index: 4
(UNM: University of New Mexico)
+ 5 AuthorsRex E. Jung38
Estimated H-index: 38
(UNM: University of New Mexico)
Published on Jan 1, 2016in Journal of Abnormal Psychology 5.52
Kristian E. Markon37
Estimated H-index: 37
,
Katherine G. Jonas4
Estimated H-index: 4
What does a structural model reflect? Different answers to this question implicitly underlie different nosological paradigms. Traditionally, structural analysis has been seen as a process of identifying true or causative values, states, or conditions. This paradigm has faced mounting challenges, however, as psychopathology theory and research has come to encompass different levels of analysis, with concomitant questions about what constructs are most "correct." Here, we discuss an alternative de...