3 Months of Nitrate plus Exercise Training Improves Hemodynamic Profile in Peripheral Arterial Disease

Peripheral artery disease (PAD) is a form of cardiovascular disease caused by atherosclerotic occlusions that impair blood flow to the lower extremities. It is characterized by endothelial dysfunction and an inability to endogenously produce nitric oxide (NO). NO bioavailability is essential for vascular health and can be increased exogenously via oral nitrate supplementation and its subsequent conversion to plasma nitrite and NO. We have...