Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality
Abstract
Resting heart rate is a heritable trait correlated with life span. Little is known about the genetic contribution to resting heart rate and its relationship with mortality. We performed a genome-wide association discovery and replication analysis starting with 19.9 million genetic variants and studying up to 265,046 individuals to identify 64 loci associated with resting heart rate (P < 5 × 10-8); 46 of these were novel. We then used the genetic...
Paper Details
Title
Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality
Published Date
Oct 31, 2016
Journal
Volume
48
Issue
12
Pages
1557 - 1563
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