Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.
Abstract
null null Background null To overcome the hurdles of cisplatin, majorly its toxicity and resistance, there has been extensive search for alternative anti-cancer metal-based compounds. Here, three Cu(II)-complexes, Cu(Sal-Gly)(phen), Cu(Sal-Gly)(pheamine), Cu(Sal-Gly)(phepoxy) are characterized for their interaction with DNA, cytotoxicity and mechanism of action. null null null Methods null The binding ability of the complexes to Calf-Thymus DNA...
Paper Details
Title
Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.
Published Date
Feb 1, 2017
Volume
1861
Issue
2
Pages
218 - 234
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Notes
History