Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.

Volume: 1861, Issue: 2, Pages: 218 - 234
Published: Feb 1, 2017
Abstract
null null Background null To overcome the hurdles of cisplatin, majorly its toxicity and resistance, there has been extensive search for alternative anti-cancer metal-based compounds. Here, three Cu(II)-complexes, Cu(Sal-Gly)(phen), Cu(Sal-Gly)(pheamine), Cu(Sal-Gly)(phepoxy) are characterized for their interaction with DNA, cytotoxicity and mechanism of action. null null null Methods null The binding ability of the complexes to Calf-Thymus DNA...
Paper Details
Title
Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.
Published Date
Feb 1, 2017
Volume
1861
Issue
2
Pages
218 - 234
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