Cognitive impairment and decline in cognitively normal older adults with high amyloid‐β: A meta‐analysis

Introduction This meta‐analysis aimed to characterize the nature and magnitude of amyloid (Aβ)‐related cognitive impairment and decline in cognitively normal (CN) older individuals. Method MEDLINE Ovid was searched from 2012 to June 2016 for studies reporting relationships between cerebrospinal fluid or positron emission tomography (PET) Aβ levels and cognitive impairment (cross‐sectional) and decline (longitudinal) in CN older adults....