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Failures in detecting HTLV-1 and HTLV-2 in patients infected with HIV-1

Published on Oct 17, 2016in AIDS Research and Human Retroviruses1.805
· DOI :10.1089/AID.2016.0191
Karoline Rodrigues Campos2
Estimated H-index: 2
,
Maria Gisele Gonçalves6
Estimated H-index: 6
,
Adele Caterino-de-Araujo8
Estimated H-index: 8
Abstract
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#2Fred Luciano Neves Santos (FIOCRUZ: Oswaldo Cruz Foundation)H-Index: 7
Last. Adele Caterino-de-AraujoH-Index: 8
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Difficulties to confirm and discriminate human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) infections by serological Western Blotting (WB) assay (HTLV Blot 2.4, MP Biomedicals) has been reported in Brazil, mainly in HIV/AIDS patients, with a large number of WB-indeterminate and WB-positive but HTLV untypeable results. Nonetheless, the line immunoassay (LIA) (INNO-LIA HTLV-I/II, Fujirebio) was pointed to enhance specificity and sensitivity for confirming HTLV-1/2 infections. To ad...
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