Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts

Volume: 15, Issue: 24, Pages: 3378 - 3389
Published: Oct 24, 2016
Abstract
Responses to human cytomegalovirus (HCMV) infection are largely individual and cell type specific. We investigated molecular profiles in 2 primary cell cultures of human fibroblasts, which are highly or marginally sensitive to HCMV infection, respectively. We screened expression of genes and microRNAs (miRs) at the early (3 hours) stage of infection. To assess molecular pathway activation profiles, we applied bioinformatic algorithms OncoFinder...
Paper Details
Title
Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts
Published Date
Oct 24, 2016
Journal
Volume
15
Issue
24
Pages
3378 - 3389
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