Chrysin induces cell apoptosis in human uveal melanoma cells via intrinsic apoptosis.
Abstract
Uveal melanoma is the most common intraocular malignant tumor in adults. Chrysin is a flavonoid present in honey, propolis, various plants and herbs. In the present study, the cytotoxic effects of chrysin were investigated on human uveal melanoma cell lines (M17 and SP6.5) and associated signaling pathways, and a comparison to the effects on normal ocular cells [scleral fibroblasts and retinal pigment epithelial (RPE) cells] was performed. The...
Paper Details
Title
Chrysin induces cell apoptosis in human uveal melanoma cells via intrinsic apoptosis.
Published Date
Dec 1, 2016
Journal
Volume
12
Issue
6
Pages
4813 - 4820
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