Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats
Abstract
Increasing evidence indicates that sirtuin 1 (SIRT1) is implicated in a wide range of cellular functions, such as oxidative stress, inflammation and apoptosis. The aim of this study was to investigate the change of SIRT1 in the brain after subarachnoid hemorrhage (SAH) and its role on SAH-induced early brain injury (EBI). In the first set of experiments, rats were randomly divided into sham group and SAH groups at 2, 6, 12, 24, 48 and 72 h. The...
Paper Details
Title
Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats
Published Date
Oct 13, 2016
Journal
Volume
7
Issue
10
Pages
e2416 - e2416
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