Preparation and in vitro investigations of triphenyl[ω-(tetrahydro-2H -pyran-2-yloxy)alkyl]tin(IV) compounds

Volume: 31, Issue: 6, Pages: e3630 - e3630
Published: Oct 4, 2016
Abstract
The reaction of SnPh3Li with X(CH2)nO–THP (THP = tetrahydro-2H-pyran-2-yl; n = 3, 4, 6, 8, 11; X = Cl, Br) afforded organotin(IV) compounds with the general formula Ph3Sn(CH2)nO–THP (1–5). The tetraorganotin(IV) compounds were characterized using multinuclear NMR and infrared spectroscopies and high-resolution mass spectrometry. Anticancer activity of the synthesized compounds was tested in vitro against the A2780 (ovarian), A549 (lung), HeLa...
Paper Details
Title
Preparation and in vitro investigations of triphenyl[ω-(tetrahydro-2H -pyran-2-yloxy)alkyl]tin(IV) compounds
Published Date
Oct 4, 2016
Volume
31
Issue
6
Pages
e3630 - e3630
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