Evaluation of total body weight and body mass index cut-offs for increased cefazolin dose for surgical prophylaxis

Volume: 48, Issue: 6, Pages: 633 - 640
Published: Dec 1, 2016
Abstract
French and American guidelines recommend increased dosage regimens of cefazolin (CFZ) for surgical prophylaxis in patients with a body mass index (BMI) ≥ 35 kg/m2 or with a total body weight (TBW) ≥ 120 kg. The objective of this study was to evaluate the accuracy of these cut-offs in identifying patients who require CFZ dose adjustment. A pharmacokinetic study was conducted in patients of varying TBW and BMI who received 2 g of CFZ intravenously...
Paper Details
Title
Evaluation of total body weight and body mass index cut-offs for increased cefazolin dose for surgical prophylaxis
Published Date
Dec 1, 2016
Volume
48
Issue
6
Pages
633 - 640
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