Original paper
Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution
Abstract
In an influential model of pattern formation, a gradient of Sonic hedgehog (Shh) signalling in the chick wing bud specifies cells with three antero-posterior positional values, which give rise to three morphologically different digits by a self-organizing mechanism with Turing-like properties. However, as four of the five digits of the mouse limb are morphologically similar in terms of phalangeal pattern, it has been suggested that...
Paper Details
Title
Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution
Published Date
Oct 1, 2016
Journal
Volume
143
Issue
19
Pages
3514 - 3521
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Notes
History