Exome sequencing in the knockin mice generated using the CRISPR/Cas system
Abstract
Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other genes, which could have unintentionally occurred during the establishment of the KI mouse line and potentially have larger impact than a point...
Paper Details
Title
Exome sequencing in the knockin mice generated using the CRISPR/Cas system
Published Date
Oct 4, 2016
Journal
Volume
6
Issue
1
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