Smc5/6 complex regulates Sgs1 recombination functions
Abstract
The family of RecQ helicases is evolutionary conserved from bacteria to humans and play key roles in genome stability. The budding yeast RecQ helicase Sgs1 has been implicated in several key processes during the repair of DNA damage by homologous recombination as part of the STR complex (Sgs1-Top3-Rmi1). Limited information on how is Sgs1 recruited and regulated at sites of damage is available. Recently, we and others have uncover a direct link...
Paper Details
Title
Smc5/6 complex regulates Sgs1 recombination functions
Published Date
Sep 23, 2016
Journal
Volume
63
Issue
3
Pages
381 - 388
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History