A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles

Volume: 73, Issue: 23, Pages: 4355 - 4381
Published: Sep 20, 2016
Abstract
The discovery of quantitative and qualitative differences of the circulating DNA (cirDNA) between healthy and diseased individuals inclined researchers to investigate these molecules as potential biomarkers for non-invasive diagnosis and prognosis of various pathologies. However, except for some prenatal tests, cirDNA analyses have not been readily translated to clinical practice due to a lack of knowledge regarding its composition, function,...
Paper Details
Title
A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles
Published Date
Sep 20, 2016
Volume
73
Issue
23
Pages
4355 - 4381
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