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Integrated supply chain network design for vaccines: a literature review

Published on Jun 1, 2014
Stef Lemmens2
Estimated H-index: 2
(Katholieke Universiteit Leuven),
Catherine Decouttere3
Estimated H-index: 3
(Katholieke Universiteit Leuven)
+ 1 AuthorsMauro Bernuzzi2
Estimated H-index: 2
(GSK: GlaxoSmithKline)
Abstract
This paper reviews the relevant literature for designing a vaccine supply chain. We show that vaccines are not like commodities and introduce the typical characteristics of a vaccine supply chain. We study the decisions at strategic, tactical and operational levels that are integrated in the research field on supply chain network design. We provide an overview of how uncertainty is incorporated in the reviewed literature by distinguishing strategic uncertainty and operational variability. Our future vaccine supply chain network needs to be sustainable, hereby taking the preferences of different stakeholders into account for obtaining a set of economical, technological and value key performance indicators that need to be satisfied by the design. This review emphasizes the need of these three types of performance criteria and shows the criteria that are described in the literature. Finally, we identify the most frequently used modeling and solution techniques and discuss the real-life applicability of the research up to now.
  • References (157)
  • Citations (1)
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References157
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#1Sheng-I Chen (Nestlé)H-Index: 10
#2Bryan A. Norman (University of Pittsburgh)H-Index: 26
Last. Shawn T. Brown (Pittsburgh Supercomputing Center)H-Index: 16
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In many developing countries, inefficiencies in the supply chain for the World Health Organization's Expanded Program on Immunization (EPI) vaccines are of grave concern; these inefficiencies result in thousands of people not being fully immunized and creates significant risk of disease epidemics. Thus, there is a great deal of interest in these countries in building tools to analyze and optimize how vaccines flow down several levels of the supply chain from manufacturers to vaccine recipients. ...
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#1Nader Azad (AUT: Amirkabir University of Technology)H-Index: 6
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Last. Morteza Shiripour (UT: University of Tehran)H-Index: 1
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In this article, we study the design problem of a reliable stochastic supply chain network in the presence of random disruptions in the location of distribution centers (DCs) and the transportation modes. It is assumed that a disrupted DC does not necessarily fail the whole of its capacity, and may lose a fraction of that, and rest of demand can be served by other DCs. We introduce a new strategy called soft-hardening strategy where the fraction of the lost capacity depends on the amount of inve...
29 CitationsSource
Multimodal transportation offers an advanced platform for more efficient, reliable, flexible, and sustainable freight transportation. Planning such a complicated system provides interesting areas in Operations Research. This paper presents a structured overview of the multimodal transportation literature from 2005 onward. We focus on the traditional strategic, tactical, and operational levels of planning, where we present the relevant models and their developed solution techniques. We conclude o...
216 CitationsSource
#1Catherine Decouttere (Katholieke Universiteit Leuven)H-Index: 3
#2Nico Vandaele (Katholieke Universiteit Leuven)H-Index: 23
Many rigorous models have been developed to support health care system design. However, embedding these models in a broader stakeholder based framework, will substantially enhance the societal and human impact. Moreover, the acceptance of the proposed health care system (re)design suggestions will be more evident. Building on the model of an NMR scanning department, we propose an integrated health care design approach to support the modelling, the stakeholder analysis, the generation of alternat...
3 CitationsSource
#1Yohanes Kristianto (University of Vaasa)H-Index: 11
#2Angappa Gunasekaran (UMassD: University of Massachusetts Dartmouth)H-Index: 67
Last. Yuqiuqe Hao (University of Vaasa)H-Index: 1
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A supply chain network design needs to consider the future probability of reconfiguration due to some problems of disaster or price changes. The objective of this article is to design a reconfigurable supply chain network by optimizing inventory allocation and transportation routing. A two-stage programming is composed according to Benders decomposition by allocating inventory in advance and anticipating the changes of transportation routings; thus the transportation routing is stochastic in nat...
48 CitationsSource
#1B. Latha Shankar (Siddaganga Institute of Technology)H-Index: 4
#2S. Basavarajappa (University B.D.T College of Engineering)H-Index: 21
Last. Jason C.H. Chen (GU: Gonzaga University)H-Index: 15
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Abstract This paper considers simultaneous optimization of strategic design and distribution decisions for three-echelon supply chain architecture consisting of following three players; suppliers, production plants, and distribution centers (DCs). The key design decisions considered are: the number and location of plants in the system, the flow of raw materials from suppliers to plants, the quantity of products to be shipped from plants to distribution centers, so as to minimize the combined fac...
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#1Hamed Mamani (UW: University of Washington)H-Index: 9
#2Stephen E. Chick (Ad: INSEAD)H-Index: 29
Last. David Simchi-Levi (MIT: Massachusetts Institute of Technology)H-Index: 51
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Influenza vaccination decisions in one country can influence the size of an outbreak in other countries due to interdependent risks from infectious disease transmission. This paper examines the inefficiency in the allocation of influenza vaccines that is due to interdependent risk of infection across borders and proposes a contractual mechanism to reduce such inefficiencies. The proposed contract is based on an epidemic model that accounts for intranational transmission and that from a source co...
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#1Kristy Buccieri (UOIT: University of Ontario Institute of Technology)H-Index: 1
#2Stephen Gaetz (York University)H-Index: 13
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#1Amir Ahmadi-Javid (AUT: Amirkabir University of Technology)H-Index: 11
#2Amir Hossein Seddighi (AUT: Amirkabir University of Technology)H-Index: 4
This paper considers a location-routing problem in a supply-chain network with a set of producer–distributors that produce a single commodity and distribute it to a set of customers. The production capacity of each producer–distributor varies randomly due to a variety of possible disruptions, and the vehicles involved in the distribution system are disrupted randomly. The goal is to determine the location, allocation and routing decisions that minimize the annual cost of location, routing and di...
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Cited By1
Newest
#1G Nafiseh Shamsi (UT: University of Tehran)
#2S. Ali Torabi (UT: University of Tehran)H-Index: 11
There are several causes such as natural or man-made disasters, malnutrition and environmental changes that may result in spread of infectious and communicable diseases which increases the risk of morbidity and mortality. Several control tools such as education and vaccination are adopted to prevent the spread of such epidemics. In this chapter, we focus on vaccination as a strong control tool and investigate the vaccine supply chains (VSCs) regarding some related challenges. The main problems o...
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