Interleukin-33 in health and disease
Abstract
Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now, evidence is accumulating that IL-33 also potently stimulates group 2 innate lymphoid cells (ILC2s), regulatory T (Treg) cells, TH1 cells, CD8+ T cells and natural killer (NK) cells. This pleiotropic nature is reflected in the role of IL-33 in tissue and metabolic...
Paper Details
Title
Interleukin-33 in health and disease
Published Date
Sep 19, 2016
Journal
Volume
16
Issue
11
Pages
676 - 689
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Notes
History