II-13 Suppression of systemic autoimmunity by the innate immune adaptor sting
Volume: 3
Published: Sep 1, 2016
Abstract
Background null Cytosolic DNA-sensing pathways that signal via the adaptor Stimulator of Interferon Genes (STING) mediate immunity to pathogens and have also been known to promote autoimmune pathology in DNAseII/III-deficient mice. However, the role of these pathways in systemic models of autoimmunity is unexplored. We hypothesised that cytosolic DNA sensing pathways contribute to the pathogenesis of autoimmune disease. Surprisingly, we report...
Paper Details
Title
II-13 Suppression of systemic autoimmunity by the innate immune adaptor sting
Published Date
Sep 1, 2016
Volume
3
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