Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules

Volume: 25, Issue: 1, Pages: 166 - 174
Published: Jan 1, 2017
Abstract
To evaluate the anti-inflammatory mechanism of action of Chondroitin Sulphate (CS).THP-1 macrophages were cultured with a range of sizes and concentrations of HA fragments with TLR4 (LPS in a physiologically relevant concentration determined by analyses of sera of a community clinic ascertained knee osteoarthritis (OA) cohort) or TLR2 (heat killed listeria bacteria) agonists and varying concentrations of CS in a physiologically relevant range...
Paper Details
Title
Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules
Published Date
Jan 1, 2017
Volume
25
Issue
1
Pages
166 - 174
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