A pediatric animal model to evaluate the effects of disuse on musculoskeletal growth and development
Abstract
Prolonged immobilization in hospitalized children can lead to fragility fractures and muscle contractures and atrophy. The purpose of this study was to develop a lower-extremity disuse rabbit model with musculoskeletal changes similar to those observed in children subjected to prolonged immobilization. Six-week-old rabbits were randomly assigned to control (CTRL, n=4) or bilateral sciatic and femoral neurectomy (bSFN, n=4) groups. Trans-axial...
Paper Details
Title
A pediatric animal model to evaluate the effects of disuse on musculoskeletal growth and development
Published Date
Oct 1, 2016
Journal
Volume
49
Issue
14
Pages
3549 - 3554
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