Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger

Young febrile infants are at substantial risk of serious bacterial infections; however, the current culture-based diagnosis has limitations. Analysis of host expression patterns ("RNA biosignatures") in response to infections may provide an alternative diagnostic approach.To assess whether RNA biosignatures can distinguish febrile infants aged 60 days or younger with and without serious bacterial infections.Prospective observational study...