Pasireotide for the Prevention of Pancreatic Fistula Following Pancreaticoduodenectomy

Objective: To determine the cost-effectiveness of perioperative administration of pasireotide for reduction of pancreatic fistula (PF). Summary: PF is a major complication following pancreaticoduodenectomy (PD), associated with significant morbidity and healthcare-related costs. Pasireotide is a novel multireceptor ligand somatostatin analogue, which has been demonstrated to reduce the incidence of PF following pancreas resection; however, the...