Genomic complexity of multiple myeloma and its clinical implications
Abstract
Multiple myeloma (MM) is a genetically complex disease that evolves from pre-malignant stages, such as monoclonal gammaopathy of undetermined significance and smouldering multiple myeloma, and progresses to symptomatic MM; this continuum provides a unique framework to study the sequential genomic evolution of MM. In the past 5 years, results from large-scale whole-exome sequencing studies have provided new insights into the clonal heterogeneity...
Paper Details
Title
Genomic complexity of multiple myeloma and its clinical implications
Published Date
Aug 17, 2016
Volume
14
Issue
2
Pages
100 - 113
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