Skeletal muscle mTORC1 regulates whole-body metabolism

Published: Jan 1, 2015
Abstract
Skeletal muscle, which represents over 40% of the total body mass, is a dynamic tissue with a key role in the maintenance of metabolic homeostasis. Several lines of evidence indicate that alterations of the normal muscle function, as for example in muscular dystrophies, obesity or diabetes, can affect the metabolism at the whole-body level (DeFronzo & Tripathy, 2009; Llagostera et al, 2007). We focused on the mTORC1 signaling pathway in skeletal...
Paper Details
Title
Skeletal muscle mTORC1 regulates whole-body metabolism
Published Date
Jan 1, 2015
Journal
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