Central sensitization as a determinant of patients’ benefit from total hip and knee replacement

Background Discrepancies exist between osteoarthritic joint changes and pain severity before and after total hip ( THR ) and knee ( TKR ) replacement. This study investigated whether the interaction between pre‐operative widespread hyperalgesia and severity of radiographic osteoarthritis ( OA ) was associated with pain severity before and after joint replacement. Methods Data were analysed from 232 patients receiving THR and 241 receiving TKR ....