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Diet, Lifestyle, Biomarkers, Genetic Factors, and Risk of Cardiovascular Disease in the Nurses’ Health Studies

Published on Sep 1, 2016in American Journal of Public Health 4.38
· DOI :10.2105/AJPH.2016.303316
Edward Yu8
Estimated H-index: 8
 , Eric B. Rimm166
Estimated H-index: 166
 + 6 AuthorsJoAnn E. Manson231
Estimated H-index: 231
Abstract
Objectives. To review the contributions of the Nurses’ Health Studies (NHSs) to the understanding of cardiovascular disease etiology in women.Methods. We performed a narrative review of the publications of the NHS and NHS II between 1976 and 2016.Results. Diets low in trans fat, saturated fat, refined carbohydrates, and sugar-sweetened beverages and rich in fruits and vegetables, whole grains, and sources of unsaturated fats are associated with reduced risk of cardiovascular disease. Healthy lifestyle choices include smoking avoidance, regular physical activity, maintaining a normal body mass index, and moderate alcohol consumption. Adherence to a combination of these healthy diet and lifestyle behaviors may prevent most vascular events. Studies also covered oral contraceptive use, postmenopausal hormone therapy, shift work, sleep duration, psychosocial factors, and various biomarkers and genetic factors. Findings, such as the association of trans fat with cardiovascular disease, have helped shaped medica...
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References44
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Published on Feb 2, 2016in JAMA 47.66
Karen B. DeSalvo3
Estimated H-index: 3
 (HHS: United States Department of Health and Human Services), Richard Olson2
Estimated H-index: 2
 (HHS: United States Department of Health and Human Services), Kellie O Casavale3
Estimated H-index: 3
 (HHS: United States Department of Health and Human Services)
This Viewpoint summarizes the updated recommendations of the US Department of Health and Human Services’ recently released 2015-2020 Dietary Guidelines for Americans.
550 Citations Source Cite
Published on Dec 15, 2015in Circulation 18.88
Ming Ding10
Estimated H-index: 10
 (Harvard University), Ambika Satija14
Estimated H-index: 14
 (Harvard University)+ 7 AuthorsFrank B. Hu202
Estimated H-index: 202
 (Harvard University)
Background—The association between consumption of caffeinated and decaffeinated coffee and risk of mortality remains inconclusive. Methods and Results—We examined the associations of consumption of total, caffeinated, and decaffeinated coffee with risk of subsequent total and cause-specific mortality among 74 890 women in the Nurses’ Health Study (NHS), 93 054 women in the Nurses’ Health Study II, and 40 557 men in the Health Professionals Follow-up Study. Coffee consumption was assessed at base...
78 Citations Source Cite
Published on Nov 16, 2015in Circulation 18.88
62 Citations Source Cite
Published on Oct 6, 2015in Journal of the American College of Cardiology 16.83
Yanping Li43
Estimated H-index: 43
 , Adela Hruby18
Estimated H-index: 18
 + 8 AuthorsBarry M. Popkin319
Estimated H-index: 319
Background The associations between dietary saturated fats and the risk of coronary heart disease (CHD) remain controversial, but few studies have compared saturated with unsaturated fats and sources of carbohydrates in relation to CHD risk.
116 Citations Source Cite
Published on Oct 1, 2015in Journal of the American College of Cardiology 16.83
Yanping Li43
Estimated H-index: 43
 (Harvard University), Adela Hruby18
Estimated H-index: 18
 (Harvard University)+ 8 AuthorsBarry M. Popkin319
Estimated H-index: 319
 (Harvard University)
Abstract Background The associations between dietary saturated fats and the risk of coronary heart disease (CHD) remain controversial, but few studies have compared saturated with unsaturated fats and sources of carbohydrates in relation to CHD risk. Objectives This study sought to investigate associations of saturated fats compared with unsaturated fats and different sources of carbohydrates in relation to CHD risk. Methods We followed 84,628 women (Nurses’ Health Study, 1980 to 2010), and 42,9...
138 Citations Source Cite
Published on Jan 1, 2015in Journal of the American College of Cardiology 16.83
Andrea K. Chomistek8
Estimated H-index: 8
 (IU: Indiana University Bloomington), Stephanie E. Chiuve44
Estimated H-index: 44
 (Harvard University)+ 3 AuthorsEric B. Rimm166
Estimated H-index: 166
 (Harvard University)
Abstract Background Overall mortality rates from coronary heart disease (CHD) in the United States have declined in recent decades, but the rate has plateaued among younger women. The potential for further reductions in mortality rates among young women through changes in lifestyle is unknown. Objectives The aim of this study was to estimate the proportion of CHD cases and clinical cardiovascular disease (CVD) risk factors among young women that might be attributable to poor adherence to a healt...
71 Citations Source Cite
Published on Oct 1, 2014in Stroke 6.24
Sally N Akarolo-Anthony12
Estimated H-index: 12
 , Monik C. Jiménez16
Estimated H-index: 16
 + 3 AuthorsKathryn M. Rexrode72
Estimated H-index: 72
Background and Purpose—Lower plasma magnesium levels may be associated with higher blood pressure and endothelial dysfunction, but sparse prospective data are available for stroke. Methods—Among 32 826 participants in the Nurses’ Health Study who provided blood samples in 1989 to 1990, incident ischemic strokes were identified and confirmed by medical records through 2006. We conducted a nested case–control analysis of 459 cases, matched 1:1 to controls on age, race/ethnicity, smoking status, da...
15 Citations Source Cite
Published on Dec 26, 2013in PLOS ONE 2.77
Dermot F. Reilly13
Estimated H-index: 13
 (MSD: Merck & Co.), Ke Hao36
Estimated H-index: 36
 (MSD: Merck & Co.)+ 2 AuthorsEric B. Rimm166
Estimated H-index: 166
 (Harvard University)
With the advance of genome-wide association studies and newly identified SNP (single-nucleotide polymorphism) associations with complex disease, important discoveries have emerged focusing not only on individual genes but on disease-associated pathways and gene sets. The authors used prospective myocardial infarction case-control studies nested in the Nurses’ Health and Health Professionals Follow-Up Studies to investigate genetic variants associated with myocardial infarction or LDL, HDL, trigl...
4 Citations Source Cite
Published on Jul 6, 2011in JAMA 47.66
Stephanie E. Chiuve44
Estimated H-index: 44
 , Teresa T. Fung42
Estimated H-index: 42
 + 4 AuthorsChristine M. Albert64
Estimated H-index: 64
Context Sudden cardiac death (SCD) accounts for more than half of all cardiac deaths; the majority of SCD events occur as the first manifestation of heart disease, especially among women. Primary preventive strategies are needed to reduce SCD incidence. Objective To estimate the degree to which adherence to a healthy lifestyle may lower the risk of SCD among women. Design, Setting, and Participants A prospective cohort study of 81 722 US women in the Nurses' Health Study from June 1984 to June 2...
128 Citations Source Cite
Published on Feb 1, 2011in The American Journal of Clinical Nutrition 6.55
Stephanie E. Chiuve44
Estimated H-index: 44
 , Ethan C. Korngold2
Estimated H-index: 2
 + 2 AuthorsChristine M. Albert64
Estimated H-index: 64
Background: Magnesium has antiarrhythmic properties in cellular and experimental models; however, its relation to sudden cardiac death (SCD) risk is unclear. Objective: We prospectively examined the association between magnesium, as measured in diet and plasma, and risk of SCD. Design: The analysis was conducted within the Nurses’ Health Study. The association for magnesium intake was examined prospectively in 88,375 women who were free of disease in 1980. Information on magnesium intake, other ...
77 Citations Source Cite
Cited By22
Newest
Published on Jun 1, 2019in Journal of Nutrition 4.40
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Published on Apr 24, 2019in European Heart Journal 23.43
Yoriko Heianza18
Estimated H-index: 18
 (Tulane University), Yan Zheng1
Estimated H-index: 1
 (Fudan University)+ 6 AuthorsLu Qi72
Estimated H-index: 72
 (Tulane University)
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Published on Apr 1, 2019in Journal of Vascular Surgery 3.29
Sandra C.P. Jansen (UM: Maastricht University), Beatrijs B.N. Hoorweg + 4 AuthorsE.V. Rouwet8
Estimated H-index: 8
 (EUR: Erasmus University Rotterdam)
Abstract Objective Cardiovascular events, such as myocardial infarction and stroke, contribute significantly to the prognosis of patients with peripheral artery disease. Therefore cardiovascular risk reduction is a vital element of treatment in patients with intermittent claudication (IC). The cardiovascular risk is largely determined by modifiable risk factors, which can be treated with medical care and lifestyle adjustments, such as increasing physical activity. The objective of this study was...
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Published on Mar 13, 2019in Journal of Rural Health 1.76
Cynthia C. Forbes8
Estimated H-index: 8
 (Dal: Dalhousie University), Zhijie Michael Yu4
Estimated H-index: 4
 (Dal: Dalhousie University)+ 6 AuthorsMelanie R. Keats6
Estimated H-index: 6
 (Dal: Dalhousie University)
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Published on Mar 1, 2019in Molecular Nutrition & Food Research 5.15
Anika Nier3
Estimated H-index: 3
 (FSU: University of Jena), Annette Brandt3
Estimated H-index: 3
 (FSU: University of Jena)+ 2 AuthorsIna Bergheim31
Estimated H-index: 31
 (FSU: University of Jena)
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Published on Feb 13, 2019in Journal of The American College of Nutrition 2.17
Michelle E. Baker (SLU: Saint Louis University), Kristen N. DeCesare (SLU: Saint Louis University)+ 3 AuthorsEdward P. Weiss28
Estimated H-index: 28
 (SLU: Saint Louis University)
AbstractObjective: Healthful dietary patterns have constituents that are known to improve exercise performance, such as antioxidants, nitrates, and alkalizing effects. However, ergogenic effects of such diets have not been evaluated. We hypothesized that a short-term Mediterranean diet results in better exercise performance, as compared to a typical Western diet.Methods: Eleven recreationally active women (n = 7) and men (n = 4) (body mass index, 24.6 ± 3.2 kg/m2; age 28 ± 3 years) were studied ...
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Published on Dec 1, 2018in Scientific Reports 4.12
Sara Nordkvist1
Estimated H-index: 1
 (Lund University), Emily Sonestedt41
Estimated H-index: 41
 (Lund University), Stefan Acosta30
Estimated H-index: 30
 (Lund University)
The research examining the association between quality of diet and abdominal aortic aneurysm (AAA) is scarce. The aim of the present study was to explore the association between diet quality and development of AAA for middle-aged individuals in the Malmo Diet and Cancer Study (MDCS), a prospective cohort study with baseline data collection carried out between 1991 and 1996. At baseline, the study participants who were eligible for this study (n = 26133) documented their dietary habits in a food ...
2 Citations Source Cite
Published on Aug 1, 2018in Clinical nutrition ESPEN
Hamid Rasad (Urmia University of Medical Sciences), Mohammad Hassan Entezari6
Estimated H-index: 6
 (IUMS: Isfahan University of Medical Sciences)+ 2 AuthorsNaseh Pahlavani (MUMS: Mashhad University of Medical Sciences)
Summary Background and aims Several studies have demonstrated that honey consumption has beneficial effects on cardiovascular disease indicators. The current study aimed to investigate the effect of honey consumption compared with sucrose on lipid profile among young healthy subjects. Methods Sixty healthy subjects, aged 18–30 years, were randomly recruited into this double blind randomized trial and assigned into two groups: honey (received 70 g honey per day) and sucrose (received 70 g sucrose...
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Published on May 1, 2018in Progress in Cardiovascular Diseases 6.75
Edward Bitok3
Estimated H-index: 3
 (LLU: Loma Linda University), Joan Sabaté45
Estimated H-index: 45
 (LLU: Loma Linda University)
Abstract There is compelling evidence showing that nut intake confers protection against cardiovascular disease (CVD). We conducted a review of the literature with respect to observational studies and randomized trials completed in the past ≈25 years that examined nut intake and CVD endpoints. We included findings from major cohort studies, a large intervention trial, and numerous smaller nut trials. Collectively, data from observational and intervention studies indicate strong and significant a...
3 Citations Source Cite
Published on Jan 8, 2018in Nature Reviews Microbiology 31.85
Jonathan Mark Brown4
Estimated H-index: 4
 (Case Western Reserve University), Stanley A Hazen20
Estimated H-index: 20
 (Cleveland Clinic)
The interplay between nutrient intake, gut microbial metabolism and microorganism-driven engagement of host receptors contributes to the pathogenesis of cardiovascular disease. In this Review, Brown and Hazen discuss the gut microbial mechanisms that drive cardiovascular disease, with special emphasis on therapeutic interventions.
28 Citations Source Cite