A 3D Toolbox to Enhance Physiological Relevance of Human Tissue Models
Abstract
We discuss the current challenges and future prospects of flow-based organoid models and 3D self-assembling scaffolds. The existing paradigm of 3D culture suffers from a lack of control over organoid size and shape; can be an obstacle for cell harvesting and extended cellular and molecular analysis; and does not provide access to the function of exocrine glands. Moreover, existing organ-on-chip models are mostly composed of 2D extracellular...
Paper Details
Title
A 3D Toolbox to Enhance Physiological Relevance of Human Tissue Models
Published Date
Sep 1, 2016
Journal
Volume
34
Issue
9
Pages
757 - 769
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