Duration of action of two insulin glargine products, LY2963016 insulin glargine and Lantus insulin glargine, in subjects with type 1 diabetes mellitus

Aims LY2963016 ( LY IGlar ) and Lantus ( IGlar ) are insulin glargine products manufactured by distinct processes, but with identical amino acid sequences. This study compared the duration of action of LY IGlar and IGlar in subjects with type 1 diabetes mellitus ( T1DM ). Materials and methods This was a randomized, double‐blind, single‐dose, two‐period, crossover study. Twenty subjects underwent 42‐hour euglycaemic clamps after a single...