Health Care’s Grand Challenge: Stimulating Basic Science on Diseases that Primarily Afflict the Poor

Perhaps the most compelling Grand Challenge in health care is addressing diseases that primarily afflict the poor. Policies and practices conceived in high-income countries for improving the lives of patients in low-income countries have been criticized as ineffective or harmful. We examine the impact of one such policy, the World Trade Organization’s 1994 Trade-Related Intellectual Property Rights (TRIPS), which was partly justified by a claim...