Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation
Abstract
Energy production in the brain depends almost exclusively on oxidative metabolism. Neurons have small energy reserves and require a continuous supply of oxygen (O2). It is therefore not surprising that one of the hallmarks of normal brain function is the tight coupling between cerebral blood flow and neuronal activity. Since capillaries are embedded in the O2-consuming neuropil, we have here examined whether activity-dependent dips in O2 tension...
Paper Details
Title
Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation
Published Date
Aug 1, 2016
Journal
Volume
91
Issue
4
Pages
851 - 862
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