Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
Abstract
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a strong genetic basis. Yet, only a small fraction of potentially causal genes-about 65 genes out of an estimated several hundred-are known with strong genetic evidence from sequencing studies. We developed a complementary machine-learning approach based on a human brain-specific gene network to present a genome-wide prediction of autism risk genes, including hundreds...
Paper Details
Title
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
Published Date
Aug 1, 2016
Journal
Volume
19
Issue
11
Pages
1454 - 1462
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