Solution Thermodynamics of highly fluorinated gemini bispyridinium surfactants for biomedical applications

Highly fluorinated gemini surfactants are relevant in pharmaceutical field, owing their ability to deliver genes to the respiratory or to the biliar epithelium, where hydrogenated interfering surfactants are present. We report for the first time the thermodynamic properties of the solutions of 1,1′-Bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2,2 n-methylenebispyridinium dichloride (n = 4, 8, 12). The gene delivery ability of the...