Biological variability of superoxide dismutase and glutathione peroxidase in blood

SUMMARYThe enzymatic antioxidant defences of mammalian cells include copper-zinc superoxide dismutase (SOD)(Cu Zn-SOD; EC 1.15.1.1) which catalyses the dismutation of superoxide anions (O2.-) to hydrogen peroxide(H2, O2)and a seleno-dependent glutathione peroxidase (GSH-px) (GSH-px; EC 1.11.1.9) which catalyses the degradation of H2O2 to H2O and O2. The measurement of these enzyme activities is often used as a possible biological index of...