Partial primary structure of bovine plasma fibronectin: Three types of internal homology (plasmin digestion/gelatin and heparin binding/interchain disulfide bridge/phosphorylation/gene multiplication)

Approximately one-half of the amino acid se- quence (911 amino acid residues out of 1,880 expected) for bovine plasma fibronectin (cold-insoluble globulin) has been determined. Three types of internal homology were identified, showing that a number of partial gene duplications (multiplications) have oc- curred during the evolution of this protein. Digestion of fibro- nectin with plasmin results in major fragments with molecular masses of 29,...