H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

We have a limited understanding of how cells mark and identify newly replicated genomic loci that have a sister chromatid; here, unmethylated K20 in the tail of new histone H4 is shown to serve as a signature of post-replicative chromatin, which is specifically recognized by the homologous recombination complex TONSL–MMS22L. We have a limited understanding of how cells mark and identify newly replicated genomic loci that have a sister chromatid....