Programming Saposin-Mediated Compensatory Metabolic Sinks for Enhanced Ubiquinone Production
Abstract
Microbial synthesis of ubiquinone by fermentation processes has been emerging in recent years. However, as ubiquinone is a primary metabolite that is tightly regulated by the host central metabolism, tweaking the individual pathway components could only result in a marginal improvement on the ubiquinone production. Given that ubiquinone is stored in the lipid bilayer, we hypothesized that introducing additional metabolic sink for storing...
Paper Details
Title
Programming Saposin-Mediated Compensatory Metabolic Sinks for Enhanced Ubiquinone Production
Published Date
Jul 14, 2016
Journal
Volume
5
Issue
12
Pages
1404 - 1411
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