The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death
Abstract
TMEM59L is a newly identified brain-specific membrane-anchored protein with unknown functions. Herein we found that both TMEM59L and its homolog, TMEM59, are localized in Golgi and endosomes. However, in contrast to a ubiquitous and relatively stable temporal expression of TMEM59, TMEM59L expression was limited in neurons and increased during development. We also found that both TMEM59L and TMEM59 interacted with ATG5 and ATG16L1, and that...
Paper Details
Title
The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death
Published Date
Jun 21, 2016
Journal
Volume
54
Issue
6
Pages
4189 - 4200
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