Gene-Proximity Models For Genome-Wide Association Studies

Published: Nov 3, 2013
Abstract
Motivated by the important problem of detecting association between genetic markers and binary traits in genome-wide association studies, we present a novel Bayesian model that establishes a hierarchy between markers and genes by defining weights according to gene lengths and distances from genes to markers. The proposed hierarchical model uses these weights to define unique prior probabilities of association for markers based on their...
Paper Details
Title
Gene-Proximity Models For Genome-Wide Association Studies
Published Date
Nov 3, 2013
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