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Electrochemically Gated Graphene Field-Effect Transistor for Extracellular Cell Signal Recording

Published on Apr 11, 2016 in DoCEIS (Doctoral Conference on Computing, Electrical and Industrial Systems)
· DOI :10.1007/978-3-319-31165-4_53
Sanaz Asgarifar2
Estimated H-index: 2
(University of the Algarve),
Henrique L. Gomes20
Estimated H-index: 20
(University of the Algarve)
+ 6 AuthorsPedro Alpuim22
Estimated H-index: 22
(University of Minho)
Abstract
This work presents an experimental characterization of electrochemically gated graphene field-effect transistors (EGFETs) to measure extracellular cell signals. The performance of the EGFETs was evaluated using cardiomyocytes cells. Extracellular signals with a peak value of 0.4 pico-amperes (pA) embedded in a noise level of 0.1 pA were recorded. Signals in current mode were compared with signals recorded as a voltage. Signals below 28 µV of magnitude can be detected in a noise floor of 7 µV with a signal-to-noise ratio of 4.
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