Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain

Volume: 6, Issue: 1
Published: Jun 20, 2016
Abstract
Recombinant adeno-associated viral (AAV) vectors have advanced to the vanguard of gene therapy. Numerous naturally occurring serotypes have been used to target cells in various tissues. There is a strong need for fast and dynamic methods which efficiently unravel viral tropism in whole organs. Ultramicroscopy (UM) is a novel fluorescence microscopy technique that images optically cleared undissected specimens, achieving good resolutions at high...
Paper Details
Title
Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain
Published Date
Jun 20, 2016
Volume
6
Issue
1
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