Twenty‐Five Year Secular Trends in Lipids and Modifiable Risk Factors in a Population‐Based Biracial Cohort: The Coronary Artery Risk Development in Young Adults (CARDIA) Study, 1985–2011

Background Cross‐sectional analyses suggest that total and low‐density lipoprotein cholesterol (LDL‐c) trends that had been declining are now reversing. We examined longitudinal data from the Coronary Artery Risk Development in Young Adults ( CARDIA ) study to examine secular trends in total cholesterol, LDL ‐c, high‐density lipoprotein cholesterol ( HDL ‐c), and triglycerides over 25 years. We also assessed whether modifiable lifestyle factors...