Leptin, Heart Disease and Exercise

3 Abstract: Obesity is a complex disorder characterized by the accumulation of excess adipose tissue. Discovery of the hormone leptin in 1994 catalyzed the field of obesity research by demonstrating the existence of a n afferent hormonal signal from adipose tissue to the central nervous system. Leptin the product of the ob gene is a proteohormone with a molecular mass of 16 kDa that is thought to play a key role in the regulation of body weight....