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Personalized Prediction of Psychosis: External Validation of the NAPLS-2 Psychosis Risk Calculator With the EDIPPP Project

Published on Oct 1, 2016in American Journal of Psychiatry13.65
· DOI :10.1176/appi.ajp.2016.15121565
Ricardo E. Carrión2
Estimated H-index: 2
(UM: University of Michigan),
Barbara A. Cornblatt40
Estimated H-index: 40
(UM: University of Michigan)
+ 9 AuthorsWilliam R. McFarlane27
Estimated H-index: 27
(UM: University of Michigan)
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Abstract
Objective:As part of the second phase of the North American Prodrome Longitudinal Study (NAPLS-2), Cannon and colleagues report, concurrently with the present article, on a risk calculator for the individualized prediction of a psychotic disorder in a 2-year period. The present study represents an external validation of the NAPLS-2 psychosis risk calculator using an independent sample of patients at clinical high risk for psychosis collected as part of the Early Detection, Intervention, and Prevention of Psychosis Program (EDIPPP).Method:Of the total EDIPPP sample of 210 subjects rated as being at clinical high risk based on the Structured Interview for Prodromal Syndromes, 176 had at least one follow-up assessment and were included in the construction of a new prediction model with six predictor variables in the NAPLS-2 psychosis risk calculator (unusual thoughts and suspiciousness, symbol coding test performance, verbal learning test performance, decline in social functioning, baseline age, and family h...
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Published on Jan 1, 2020
Thomas E. Smith20
Estimated H-index: 20
(Columbia University),
Lisa B. Dixon54
Estimated H-index: 54
(Columbia University)
Early intervention services for psychotic disorders were first tested in Australia and Europe in the 1990s. These efforts stimulated interest to develop early intervention programs in the United States and in 2016 the National Institute of Mental Health identified a treatment model called Coordinated Specialty Care (CSC). This team-based approach includes psychotherapy, medication management, family education and support, case management, and work or education support, and is the foundation for ...
Published on Feb 12, 2019in Scientific Reports4.01
Jin Hee Lee (Yonsei University), Ho Jang + 1 AuthorsSeongho Min4
Estimated H-index: 4
(Yonsei University)
Suicide is a leading cause of death among adolescents and a major public health concern. Here we developed a risk stratification model for adolescent suicide attempts using sociodemographic characteristics, risk behaviours and psychological variables. Participants were 247,222 subjects in the Korea Youth Risk Behavior Web-based Survey (KYRBS). We developed a suicide index based on the suicide risk estimated in the generalized linear model and proposed the risk stratification model using the R la...
Published on Jun 1, 2019in Community Mental Health Journal1.46
Alex S. Cohen57
Estimated H-index: 57
(LSU: Louisiana State University),
Taylor L. Fedechko1
Estimated H-index: 1
(LSU: Louisiana State University)
+ 6 AuthorsBrita Elvevåg13
Estimated H-index: 13
(University of Tromsø)
Accurate prediction of risk-states in Serious Mental Illnesses (SMIs) is critical for reducing their massive societal burden. Risk-state assessments are notably inaccurate. Recent innovations, including widely available and inexpensive mobile technologies for ambulatory “biobehavioral” data, can reshape risk assessment. To help understand and accelerate clinician involvement, we surveyed 90 multi-disciplinary clinicians serving SMI populations in various settings to evaluate how risk assessment ...
Published on Sep 19, 2019in Psychological Medicine5.64
Evangelos Vassos26
Estimated H-index: 26
,
Pak Sham106
Estimated H-index: 106
+ 7 AuthorsCraig Morgan56
Estimated H-index: 56
Published on Jun 1, 2019in Psychiatry Research-neuroimaging2.21
K. Juston Osborne3
Estimated H-index: 3
(NU: Northwestern University),
Vijay Anand Mittal25
Estimated H-index: 25
(NU: Northwestern University)
Abstract Early identification of individuals likely to develop psychosis is a priority for the field, resulting in the development of risk calculators that provide personalized estimates that an individual at clinical high-risk (CHR) will develop psychosis. The North American Prodrome Longitudinal Study (NAPLS) consortium and Shanghai At-Risk for Psychosis program have recently developed such calculators (NAPLS-2/SIPS-RC, respectively), but their discrimination performance has never been examine...
Published on 2019in Schizophrenia Bulletin7.29
Erich Studerus17
Estimated H-index: 17
(University of Basel),
Katharina R. Beck4
Estimated H-index: 4
(University of Basel)
+ 1 AuthorsA Riecher-Rssler54
Estimated H-index: 54
(University of Basel)
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