N-acetylcysteine treatment blocks the development of ethanol-induced behavioural sensitization and related ΔFosB alterations
Abstract
Ethanol addiction is a serious public health problem that still needs more effective pharmacological treatment. A key factor in the development and maintenance of this disease is the advent of neuroadaptations in the mesocorticolimbic brain pathway upon chronic ethanol abuse. In general, these neuroadaptations are maladaptive and affect numerous neurotransmitter systems and intracellular molecules. One of these molecules is ΔFosB, a...
Paper Details
Title
N-acetylcysteine treatment blocks the development of ethanol-induced behavioural sensitization and related ΔFosB alterations
Published Date
Nov 1, 2016
Journal
Volume
110
Pages
135 - 142
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